科学研究 |
代表性论文(5篇) [1] Brecher M, Li Z, Liu B, Zhang J, Koetzner CA, Alifarag A, Jones SA, Lin Q, Kramer LD, Li H*, A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease. PLoS Pathog. 2017 May 25;13(5):e1006411. [2] Li Z, Brecher M, Deng YQ, Sakamuru S, Liu B, Huang R, Koetzner CA, Allen CA, Jones SA, Chen H, Zhang NN, Tian M, Gao F, Lin Q, Banavali N, Zhou J6, Boles N, Xia M, Kramer LD, Qin CF, Li H*. Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction. Cell Res. 2017 Aug;27(8):1046-1064. [3] Brecher M, Chen H, Liu B, Banavali NK, Jones SA, Zhang J, Li Z, Kramer LD, Li H*. Novel Broad Spectrum Inhibitors Targeting the Flavivirus Methyltransferase. PLoS One. 2015 Jun 22;10(6):e0130062. [4] Brecher M, Chen H, Liu B, Banavali NK, Jones SA, Zhang J, Li Z, Kramer LD, Li H*, Refolding of a fully functional flavivirus methyltransferase revealed that S-adenosyl methionine but not S-adenosyl homocysteine is copurified with flavivirus methyltransferase. Protein Sci. 2015 Jan;24(1):117-28. [5] Liu B, Mark Bartlam, Renjun Gao, Weihong Zhou, Hai Pang, Yiwei Liu, Yan Feng &Zihe Rao. Crystal structure of the Hyperthermophilic Inorganic Pyrophosphatase from the Archaeon Pyrococcus horikoshii. Biophysical Journal (2004)86 (1 Pt 1) : 420-427 |