代表性科研项目(5项) [1] 国家自然科学基金青年项目:高良姜素乳液微结构介导FPN泵铁效应调控肠铁稳态的分子机制,2025-2027,国家自然科学基金委员会 [2] 广东省基础与应用基础研究基金项目:基于生物节律蛋白BMAL1调控铁死亡途径解析高良姜素缓解酒精性肝损伤的分子作用机制研究,2024-2027,广东省自然科学基金委员会 代表性论文(5篇) [1] Yanan Zhao; Jing Lu; Ankang Mao; Ranran Zhang; Shuang Guan. Autophagy Inhibition Plays a Protective Role in Ferroptosis Induced by Alcohol via the p62–Keap1–Nrf2 Pathway, Journal of Agricultural and Food Chemistry, 2021, 69(33): 9671-9683 [2] Yanan Zhao; Ranran Zhang; Ziyi Wang; Ziheng Chen; Guang Wang; Shuang Guan; Jing Lu. Melatonin Prevents against Ethanol-Induced Liver Injury by Mitigating Ferroptosis via Targeting Brain and Muscle ARNT-like 1 in Mice Liver and HepG2 Cells, Journal of Agricultural and Food Chemistry, 2022, 7(40): 12953-12967 [3] Zhao Y, Li B, Liu J, Chen L, Teng H. Galangin Prevents Against Ethanol-Induced Intestinal Barrier Dysfunction and NLRP3 Inflammasome Activation via NF-κB/MAPK Signaling Pathways in Mice and Caco-2 Cells. J Agric Food Chem. 2024 Apr 11. [4] Yanan Zhao; Ranran Zhang; Ziheng Chen; Ziyi Wang; Shuang Guan; Jing Lu. Protective effect of brain and muscle arnt-like protein-1 against ethanol-induced ferroptosis by activating Nrf2 in mice liver and HepG2 cells, Food Science and Human Wellness, 2023, 12(6): 2390-2407. [5] Yanan Zhao; Ankang Mao; Ranran Zhang; Shuang Guan; Jing Lu. SIRT1/mTOR pathway-mediated autophagy dysregulation promotes Pb-induced hepatic lipid accumulation in HepG2 cells, Environmental Toxicology, 2021, 37(3): 549-563 |