科学研究 |
代表性科研项目 [1]国家自然科学基金青年科学基金项目,基于超分子化学作用的姜黄多酚抗肿瘤分子机制研究(21602034),2017/01-2019/12, 主持 [2]广东省自然科学基金博士启动项目,姜黄素超分子包合物的抗肿瘤活性评价及其作用机理研究(2016A030310332),2016/6-2019/6, 主持 [3]广东省自然科学基金面上项目,姜黄素超分子包合物对肝细胞氧化损伤的保护作用机制研究(2020A1515010860),2020/1-2022/12, 主持 [4]广东省自然科学基金面上项目,姜黄素超分子包合物逆转酒精性肝损伤的分子作用机制(2021A1515012455),2021/1-2023/12, 主持 [5]湛江市科技计划项目,马尾藻岩藻聚糖硫酸酯的抗肿瘤活性评价及其作用机理研究(2020A01034),2020/9-2022/9, 主持 代表性论文 [1] Chen Yanzhe, Zhu Feifei, Chen Jianping(通讯作者), Liu Xiaofei, Li Rui, Wang Zhuo, Cheong, Kit -Leong, Zhong Saiyi. Selenium nanoparticles stabilized by Sargassum fusiforme polysaccharides: Synthesis, characterization and bioactivity. International Journal of Biological Macromolecules, 2024, 269(1):132073. (JCR 一区top) [2] Chen Jianping, Chen Xuehua, Tang Anqi, Wang Zhuo, Cheong, Kit -Leong, Liu Xiaofei, Zhong Saiyi. Chondroitin sulfate-functionalized selenium nanoparticle-induced S-phase cell cycle arrest and apoptosis in HeLa Cells. Journal of Food Science, 2024, 89(7):4460-4479. (JCR 一区) [3] Chen, Jianping; Fan, Tugui, Li, Jiarui, Li, Rui, Liu, Xiaofei, Wu, Bing, Gao, Jialong, Liu, Ying, Dong, Hao, Zhong, Saiy. Curcumin/cyclodextrin polymer inclusion complex attenuates ethanol-i nduced liver injury by inhibition of DNA damage in mice. Food Science & Nutrition, 2023, 11(5), 2418-2426. (JCR 二区) [4] Li Jiarui, Wang Zhuo, Chen Jianping(通讯作者), Luo Baozhen, Chen Xuehua, Li Rui, Gao Jialong, Liu Xiaofei, Song Bingbing, Zhong Saiyi. Protective effect of Sargassum fusiforme polysaccharides on H2O2-induced injury in LO2 cells. Frontiers in Marine Science, 2023, 9:1098758. (JCR 一区) [5] Luo Baozhen; Wang Zhuo; Chen, Jianping(通讯作者); Chen Xuehua; Li Jiarui; Li Yinghua; Li Rui; Liu Xiaofei; Song Bingbing; Cheong Kit-Leong; Zhong Saiyi. Physicochemical Characterization and Antitumor Activity of Fucoidan and Its Degraded Products from Sargassum hemiphyllum (Turner) C. Agardh. Molecules 2023, 28, 2610. (JCR 一区top) 代表性授权专利 [1] 陈建平, 陈彦哲, 刘晓菲, 汪卓, 刘颖,李瑞,钟赛意. 羊栖菜多糖纳米硒的制备方法及在制备抗肿瘤药物中的应用, ZL202410281870.4, 2024-06-21. [2] Chen Jianping, Qin Xiaoming, Zhong Saiyi, Liu Hai, Liu Ying, Cao Xiaohuang, Chen Suhua. Preparation method of curcumin-cyclodextrin supramolecular inclusion compound, 2020101225, 2020.07.02. [3] Chen Jianping, Qin Xiaoming, Zhong Saiyi, Liu Ying, Liang Yuanwei. Temperature sensitive gel of curcumin clathrate and preparation method and application thereof, 2022/03103, 2022.05.25 |